The EUROLINE ANA Profile 5 (IgG) test kit provides a qualitative for human autoantibodies of the IgG class to 18 different antigens nRNP/Sm, Sm, RNP 70, -A, -C, SS-A (native), Ro-52, SS-B, Scl-70, PM-Scl, Jo-1, CENP B, PCNA, dsDNA, nucleosomes, histones, ribosomal P-protein and AMA M2 in serum or plasma for the diagnosis of Sharp syndrome (MCTD), systemic lupus erythematosus (SLE), Sjögren’s syndrome, progressive systemic sclerosis, poly-/dermatomyositis, overlap syndromes, limited form of progressive systemic sclerosis (CREST syndrome) and primary biliary cholangitis.