The EUROLINE-FOOD Profile 108 (IgG) test provides semiquantitative determination of the food-specific immunoglobulin class IgG in serum or plasma and contributes to the diagnosis of intolerances against foods and food additives.
The test enables the diagnosis of sensitisations against foods and food additives which may lead to unspecific health problems (e.g. gastrointestinal disorders, inflammatory skin diseases, migraine, chronic fatigue syndrome, etc.). These symptoms may be caused by aberrant immune reactions which cause a measurable rise in the IgG concentration.
The Anti-Sa ELISA (IgG) test kit provides a semiquantitative or quantitative assay for the determination of human autoantibodies of the IgG class in human serum against Sa for the diagnosis of rheumatoid arthritis.
The EUROLINE Food "Ukraine 2" (IgE) test kit is designed for semiquantitative determination of allergen- specific IgE (sIgE) in serum or plasma, contributing to the diagnosis of allergies.
The test kit is used for the diagnosis of sensitisations that may lead to allergy-associated symptoms such as conjunctivitis, rhinitis, urticaria or gastrointestinal problems. These symptoms can be caused by misguided immune reactions leading to increased immunoglobulin class E (IgE) antibody concentrations, which are measured by using this test.
The EUROLINE Neuronal Antigens Profile 2 (IgG) test kit provides a qualitative assay for human autoantibodies of the immunoglobulin class IgG to the 6 different antigens amphiphysin, CV2, PNMA2 (Ma2/Ta), Ri, Yo and Hu in serum or plasma for the diagnosis of paraneoplastic neurological syndromes (PNS).
The EUROLINE Anti-SOX1, -Titin (IgG) test kit provides a qualitative assay for human autoantibodies of the immunoglobulin class IgG to the antigens SOX1 and titin in serum or plasma for the diagnosis of paraneoplastic neurological syndromes (PNS).
The EUROLINEParaneoplastic Neurologic Syndromes 12 Ag (IgG) test kit provides qualitative determination of human autoantibodies of the immunoglobulin class IgG to 12 different antigens: amphiphysin, CV2, PNMA2 (Ma2/Ta), Ri, Yo, Hu, recoverin, SOX1, titin, zic4, GAD65 and Tr (DNER) in serum or plasma to support the diagnosis of paraneoplastic neurological syndromes (PNS).
The EUROLINE Anti-Gangliosides Profile 1 (IgG) test kit provides a qualitative assay for human autoantibodies of the immunoglobulin class IgG to the three gangliosides GM1, GD1b and GQ1b in serum or plasma for the diagnosis of Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), multifocal motor neuropathy (MMN), sensory neuropathy and Miller-Fisher syndrome (MFS; a subtype of GBS).
The EUROLINE Anti-Gangliosides Profile 2 (IgG) test kit provides a qualitative assay for human autoantibodies of the immunoglobulin class IgG to the seven gangliosides GM1, GM2, GM3, GD1a, GD1b, GT1b and GQ1b in serum or plasma for the diagnosis of Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), multifocal motor neuropathy (MMN), sensory neuropathy and Miller-Fisher syndrome (MFS; a subtype of GBS).
The EUROLINE Anti -MPO, -PR3 and -GBM (IgG) test kit provides a qualitative assay for human antibodies of the immunoglobulin class IgG against the 3 different antigens myeloperoxidase (MPO), proteinase 3 (PR3) and glomerular basement membrane (GBM antigens) in serum or plasma for the diagnosis of granulomatosis with polyangiitis (Wegener’s) (GPA), microscopic polyarteritis and Goodpasture syndrome.
The EUROLINE Liver Profile (IgG) test kit provides a qualitative assay for human autoantibodies of the immunoglobulin class IgG to four different antigens: AMA-M2 (pyruvate-dehydrogenase-complex), LKM-1 (liver-kidney microsomes; cytochrome P450 II D6), LC-1 (cytosolic liver antigen type 1; formiminotransferase-cyclodeaminase) and SLA/LP (soluble liver antigen/liver-pancreas antigen) in serum or plasma for the diagnosis of primary biliary liver cirrhosis (PBC), in case of an increase in transaminases for unclear reasons and suspected cases of autoimmune hepatitis (AIH).
The EUROLINE Autoimmune Liver Diseases (IgG) test kit provides a qualitative assay for human autoantibodies of the immunoglobulin class IgG to 9 different antigens: AMA-M2 (pyruvate-dehydrogenase-complex), M2-3E (BPO, fusion protein of the E2 subunits of the alpha-2-oxoacid dehydrogenases of the inner mitochondrial membrane), Sp100 (nuclear granula protein, nuclear dots), PML (promyelocytic leukaemia protein, nuclear dots), gp210 (integral protein of the nuclear membrane, nuclear pore complex), LKM-1 (liver-kidney microsomes; cytochrome P450 II D6), LC-1 (cytosolic liver antigen type 1; formiminotransferase-cyclodeaminase), SLA/LP (soluble liver antigen/liver-pancreas antigen) and Ro-52 in serum or plasma for the diagnosis of primary biliary liver cirrhosis, increase in transaminases for unclear reasons, suspected autoimmune hepatitis.
The EUROLINE Myositis Antigens Profile (IgG) test kit provides a qualitative assay for human autoantibodies of the IgG class to 7 different antigens: Mi-2β, Ku, PM-Scl, Jo-1, PL-7, PL-12 and Ro-52 in serum or plasma for the diagnosis of dermato- and polymyositis, idiopathic myositis and antisynthetase syndrome.
The EUROLINE Systemic sclerosis (Nucleoli) profile (IgG)test kit provides a qualitative assay for human autoantibodies of the immunoglobulin class IgG to the 13 different antigens Scl-70, CENP A, CENP B, RP11 and RP155 (RNA Polymerase III subunits), fibrillarin, NOR90, Th/To, PM-Scl100, PM-Scl75, Ku, PDGFR (platelet derived growth factor receptor) and Ro-52 in serum or plasma for the diagnosis of progressive systemic sclerosis (SSc, diffuse and limited form) and overlap syndromes.
The Osteoprotegerin (OPG) ELISA kit is a sandwich ELISA intended for the quantitative determination of osteoprotegerin in serum, EDTA plasma, heparin plasma or citrate plasma.
Osteoprotegerin (OPG) or osteoclast inhibitory factor (OCIF) is a glycoprotein produced by many different tissues and cell types including osteoblasts.
OPG is a negative regulator of bone resorption by acting as decoy receptor for RANKL, thus neutralizing its function in osteoclastogenesis. This glycoprotein is also involved in the regulation of vascular calcification.
The total sRANKL (human) ELISA kit is intended for the quantitative determination of of total sRANKL (human)
in serum and plasma, i.e. free sRANKL as well as sRANKL bound to
OPG.
Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) is a transmembrane protein produced by osteocytes and is part of the tumor necrosis factor (TNF) family. It is the main stimulant for osteoclast formation and is essential for their survival.
RANKL expression leads to bone reabsorption and loss which is counteracted by osteoprotegerin (OPG). RANKL/OPG regulate bone remodeling and an imbalance may lead to bone metabolic diseases.