The Zonulin ELISA kit is intended for the quantitative determination of zonulin family peptides (ZFP) in stool.
Zonulin is a human protein which regulates tight junctions of the digestive tract. Zonulin binds to a specific receptor on the surface of intestinal epithelia and triggers a cascade of biochemical events which induces tight junction disassembly and a subsequent permeability increase of the intestinal epithelia, allowing some substances to pass through and activate immune reactions.
The zonulin system is more activated in celiac disease and type 1 diabetes mellitus patients.
An increased intestinal permeability, also colloquially called ‘leaky gut’, is nowadays associated with the metabolic syndrome, obesity, and several autoimmune, inflammatory, and neoplastic diseases.
Наборы реагентов | |
Test method | Manual / Automatic |
POC-test | No |
Using by a doctor | No |
Общие | |
Storage conditions | 2 - 8 ℃ |
Country of Origin | Germany |
Average Delivery Time | 3 weeks |
Tags: Пищеварительная система Пищеварительная система Пищеварительная система ELISA ELISA ELISA Стул Стул Стул