1,25 (OH) 2 Vitamin D ELISA

The 1,25 (OH) 2 Vitamin D ELISA Kit is intended for the quantitative determination of 1,25-dihydroxyvitamin D in serum and plasma. 

1,25 (OH) 2 Vitamin D is formed in a second hydroxylation step in the kidney. The responsible enzyme, the kidney 1α-hydroxylase, is subjected to a rigid control through hormones (especially parathyroid hormone) and its activity is influenced by the serum concentrations of calcium and phosphate.

Indications:

• Defect of kidney function
• Chronic kidney failure
• Haemodialysis following kidney transplantation
• Renal osteopathy
• Osteomalacia from various types of vitamin D metabolism disturbances
• Kidney tubules function disturbances (diabetes insipidus, Fanconi-Syndrom)
• Monitoring of therapy with active vitamin D metabolites
• Ideopathic hypercalciuria
• Hypercalcaemia