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The Retinol-binding protein RBP/RBP4 ELISA kit is an enzyme immunoassay intended for the quantitative determination of free retinol-binding protein RBP/RBP4 as well as RBP4 complexed with transthyretin in plasma, serum and urine. 

Retinol-binding protein RBP/RBP4 is a transport protein for vitamin A which forms a complex with prealbumin in blood, but loses its affinity for prealbumin once the vitamin has been delivered to the target cells. The free RBP/RBP4 molecule is rapidly filtered at the glomerulus and catabolised in the renal tubules after resorption by the proximal tubular cells. In kidney disease with prevailing tubular changes, these proteins are not reabsorbed and appear in the urine. 

The elevation of serum RBP/RBP4 causes systemic insulin resistance, whereas its reduction improves the insulin action.

The Retinol-binding protein RBP/RBP4 ELISA kit is an enzyme immunoassay intended for the quantitative determination of free retinol-binding protein RBP/RBP4 as well as RBP4 complexed with transthyretin in plasma, serum and urine. 

Retinol-binding protein RBP/RBP4 is a transport protein for vitamin A which forms a complex with prealbumin in blood, but loses its affinity for prealbumin once the vitamin has been delivered to the target cells. The free RBP/RBP4 molecule is rapidly filtered at the glomerulus and catabolised in the renal tubules after resorption by the proximal tubular cells. In kidney disease with prevailing tubular changes, these proteins are not reabsorbed and appear in the urine. 

The elevation of serum RBP/RBP4 causes systemic insulin resistance, whereas its reduction improves the insulin action.

The Adiponectin (total) ELISA kit is an enzyme immunoassay intended for the quantitative determination of adiponectin in serum and plasma. 

Adiponectin levels are associated with insulin resistance and, accordingly, are associated with type 2 diabetes. The higher the level of adiponectin in the blood, the lower the risk of developing type 2 diabetes, regardless of body mass index (BMI), race and gender.

In addition, it is involved in inflammatory processes and, therefore, is important for the development of atherosclerosis and coronary artery disease.

The Intact Proinsulin ELISA Kit is an enzyme immunoassay intended for the quantitative determination of intact proinsulin in serum and plasma.

Proinsulin is a precursor molecule for insulin and is synthesised by the pancreatic β-cells.

Indications:

• Diabetes type 1 and 2;

• Insulinomas, functional hypoglycemia, hyperinsulinemia;

• Kidney dysfunction, cirrhosis and hyperthyreosis;

• Cardiovascular diseases.

The Anti ox-LDL ELISA kit is an enzyme immunoassay intended for the quantitative determination of ox-LDL antibodies in EDTA-plasma and serum. 

Elevated plasma levels of oxidized LDL are associated with a higher cardiovascular risk and a higher incidence of metabolic diseases, i.e., metabolic syndrome, obesity and type 2 diabetes. Subclinical atherosclerosis, kidney and liver diseases are also associated with elevated levels of oxidized LDL.

The Vitamin B1 kit is a microtiter plate test kit based on a microbiological method which measures the total vitamin B1 content in whole blood using a Lactobacillus fermentum coated microtiter plate. For use in human and veterinary medicine and in research.

Vitamin B1 deficiency may lead to beriberi, characterised by nerve, heart, and brain abnormalities.

Deficiency may occur in alcoholics or in special clinical situations such as hemodialysis, chronic peritoneal dialysis, or after administration of glucose to a vitamin B1-depleted patient. Further vitamin B1 deficiency diseases are Wernicke‘s encephalopathy, Korsakow syndrome, and some forms of Landry‘s paralysis. Myopathy also was found in relation to thiamine deficiency.

The Relaxin ELISA kit is an enzyme immunoassay intended for the quantitative determination of Relaxin in serum, plasma, urine, seminal plasma and tissue samples.

Relaxin is a peptide hormone, it's main function is the relaxation of smooth musculature. The level of relaxin increase during ovulation and pregnancy.

Also relaxin:

• promotes dilation of blood vessels in several organs and tissues, including the uterus, the mammary gland, the lung and the heart;
• has a chronotropic action on the heart;
• nhibits the stimulation of endothelin-1, the most potent vasoconstrictor in heart failure;
• inhibits the release of histamine by mast cells, thus being able to counteract experimental allergic asthma; 
• depresses aggregation of platelets and their release by megakaryocytes;
  
• influences the secretion of hormones by the pituitary gland;
• contributes to the regulation of fluid balance.