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The Retinol-binding protein RBP/RBP4 ELISA kit is an enzyme immunoassay intended for the quantitative determination of free retinol-binding protein RBP/RBP4 as well as RBP4 complexed with transthyretin in plasma, serum and urine. 

Retinol-binding protein RBP/RBP4 is a transport protein for vitamin A which forms a complex with prealbumin in blood, but loses its affinity for prealbumin once the vitamin has been delivered to the target cells. The free RBP/RBP4 molecule is rapidly filtered at the glomerulus and catabolised in the renal tubules after resorption by the proximal tubular cells. In kidney disease with prevailing tubular changes, these proteins are not reabsorbed and appear in the urine. 

The elevation of serum RBP/RBP4 causes systemic insulin resistance, whereas its reduction improves the insulin action.

The Retinol-binding protein RBP/RBP4 ELISA kit is an enzyme immunoassay intended for the quantitative determination of free retinol-binding protein RBP/RBP4 as well as RBP4 complexed with transthyretin in plasma, serum and urine. 

Retinol-binding protein RBP/RBP4 is a transport protein for vitamin A which forms a complex with prealbumin in blood, but loses its affinity for prealbumin once the vitamin has been delivered to the target cells. The free RBP/RBP4 molecule is rapidly filtered at the glomerulus and catabolised in the renal tubules after resorption by the proximal tubular cells. In kidney disease with prevailing tubular changes, these proteins are not reabsorbed and appear in the urine. 

The elevation of serum RBP/RBP4 causes systemic insulin resistance, whereas its reduction improves the insulin action.

The Adiponectin (total) ELISA kit is an enzyme immunoassay intended for the quantitative determination of adiponectin in serum and plasma. 

Adiponectin levels are associated with insulin resistance and, accordingly, are associated with type 2 diabetes. The higher the level of adiponectin in the blood, the lower the risk of developing type 2 diabetes, regardless of body mass index (BMI), race and gender.

In addition, it is involved in inflammatory processes and, therefore, is important for the development of atherosclerosis and coronary artery disease.

The Intact Proinsulin ELISA Kit is an enzyme immunoassay intended for the quantitative determination of intact proinsulin in serum and plasma.

Proinsulin is a precursor molecule for insulin and is synthesised by the pancreatic β-cells.

Indications:

• Diabetes type 1 and 2;

• Insulinomas, functional hypoglycemia, hyperinsulinemia;

• Kidney dysfunction, cirrhosis and hyperthyreosis;

• Cardiovascular diseases.

The Mosaic: Pancreas (Monkey)/Cerebellum (Monkey) IIFT test kit is designed for the qualitative or semiquantitative determination of human antibodies of immunoglobulin classes IgG against ICA and GAD in serum or plasma for the diagnosis of  diabetes mellitus type 1 (insulin-dependent diabetes mellitus, IDDM). 

The Pancreas (Monkey) IIFT test kit is designed exclusively for the qualitative or quantitative determination of exclusively human antibodies in human serum or plasma for the diagnosis of type I diabetes.