Nitrotyrosin ELISA

The Nitrotyrosine ELISA kit is an enzyme immunoassay intended for the quantitative determination of protein-bound nitrotyrosine in human EDTA-plasma, serum and dried blood spots. 

The accumulation of protein bound nitrotyrosine is associated with cardiovascular diseases that are based on inflammatory processes (e. g., atherosclerosis, myocardial infarction, diabetic vasculopathy, hypertension, or coronary heart diseases).

A growing number of studies have also associated the accumulation of nitrotyrosine with neurological diseases (Alzheimer´s disease, Parkinson´s disease, multiple sclerosis, stroke). 

Nitrotyrosine is a stable product and might be seen as a correlate of peroxynitrite production, and its accumulation in cells and tissues is a marker of oxidative stress and nitrosative stress, respectively.